COVID-19 Treatments: Clinical Outcomes Results Extracted from Randomized Controlled Trials
||Certainty/Quality of Evidence
||Does not appear to reduce mortality. Insufficient data to suggest clinical efficacy. Data suggests some adverse events (such as diarrhea).
||4 trials (up to 4,674 patients)
||Possible acceleration of clinical improvement by 2-4 days. Possible reduction in death or mechanical ventilation at 2 weeks.
||2 trials (up to 1,299 patients)
||May reduce mortality, chance of needing a ventilator, or still being in the hospital at 28 days in subgroup of patients who need respiratory support (oxygen or ventilator).
||1 trial (6,425 patients)